https://en.wikipedia.org/wiki/Median_lethal_dose#Limitation

Substance Animal, Route LD50
{LC50}
LD50 : g/kg
{LC50 : g/L}
standardized
Reference
Water rat, oral >90g/kg >90 [6]
Sucrose (table sugar) rat, oral 29,700 mg/kg 29.7 [7]
Glucose (blood sugar) rat, oral 25,800 mg/kg 25.8 [8]
Monosodium glutamate (MSG) rat, oral 16,600 mg/kg 16.6 [9]
Stevioside (from stevia) mice & rats, oral >15,000 mg/kg 15 [10]
Vitamin C (ascorbic acid) rat, oral 11,900 mg/kg 11.9 [11]
Lactose (milk sugar) rat, oral >10,000 mg/kg 10.0 [12]
Aspartame mice, oral >10,000 mg/kg 10.0 [13]
Urea rat, oral 8,471 mg/kg 8.471 [14]
Cyanuric acid rat, oral 7,700 mg/kg 7.7 [15]
Cadmium sulfide rat, oral 7,080 mg/kg 7.08 [16]
Ethanol (Grain alcohol) rat, oral 7,060 mg/kg 7.06 [17]
Sodium isopropyl methylphosphonic acid (IMPA, metabolite of sarin) rat, oral 6,860 mg/kg 6.86 [18]
Melamine rat, oral 6,000 mg/kg 6 [15]
Methanol rat, oral 5,628 mg/kg 5.628 [19]
Taurine rat, oral >5,000 mg/kg 5.0 [20]
Melamine cyanurate rat, oral 4,100 mg/kg 4.1 [15]
Fructose (fruit sugar) rat, oral 4,000 mg/kg 4 [21]
Sodium molybdate rat, oral 4,000 mg/kg 4 [22]
Sodium chloride (table salt) rat, oral 3,000 mg/kg 3 [23]
Paracetamol (acetaminophen) rat, oral 1,944 mg/kg 1.944 [24]
Delta-9-tetrahydrocannabinol (THC) rat, oral 1,270 mg/kg 1.27 [25]
Cannabidiol (CBD) rat, oral 980 mg/kg 0.98 [26]
Methamphetamine rat, oral 980 mg/kg 0.98 [27]
Metallic Arsenic rat, oral 763 mg/kg 0.763 [28]
Ibuprofen rat, oral 636 mg/kg 0.636 [29]
Formaldehyde rat, oral 600–800 mg/kg 0.600 [30]
Alkyl dimethyl benzalkonium chloride (ADBAC) rat, oral
fish, immersion
aq. invertebrates, imm.
304.5 mg/kg
{0.28 mg/L}
{0.059 mg/L}
0.3045
{0.00028}
{0.000059}
[31]
Coumarin (benzopyrone, from Cinnamomum aromaticum and other plants) rat, oral 293 mg/kg 0.293 [32]
Psilocybin (from magic mushrooms) mouse, oral 280 mg/kg 0.280 [33]
Hydrochloric acid rat, oral 238–277 mg/kg 0.238 [34]
Ketamine rat, intraperitoneal 229 mg/kg 0.229 [35]
Aspirin (acetylsalicylic acid) rat, oral 200 mg/kg 0.2 [36]
Caffeine rat, oral 192 mg/kg 0.192 [37]
Arsenic trisulfide rat, oral 185–6,400 mg/kg 0.185–6.4 [38]
Sodium nitrite rat, oral 180 mg/kg 0.18 [39]
Methylenedioxymethamphetamine (MDMA, ecstasy) rat, oral 160 mg/kg 0.18 [40]
Uranyl acetate dihydrate mouse, oral 136 mg/kg 0.136 [41]
Dichlorodiphenyltrichloroethane (DDT) mouse, oral 135 mg/kg 0.135 [42]
Bisoprolol mouse, oral 100 mg/kg 0.1 [43]
Cocaine mouse, oral 96 mg/kg 0.096 [44]
Cobalt(II) chloride rat, oral 80 mg/kg 0.08 [45]
Cadmium oxide rat, oral 72 mg/kg 0.072 [46]
Thiopental sodium (used in lethal injection) rat, oral 64 mg/kg 0.064 [47]
Sodium fluoride rat, oral 52 mg/kg 0.052 [48]
Pentaborane human, oral <50 mg/kg <0.05 [49]
Capsaicin mouse, oral 47.2 mg/kg 0.0472 [50]
Mercury(II) chloride rat, dermal 41 mg/kg 0.041 [51]
Vitamin D3 (cholecalciferol) rat, oral 37 mg/kg 0.037 [52]
Piperidine (from black pepper) rat, oral 30 mg/kg 0.030 [53]
Heroin (diamorphine) mouse, intravenous 21.8 mg/kg 0.0218 [54]
Lysergic acid diethylamide (LSD) rat, intravenous 16.5 mg/kg 0.0165 [55]
Arsenic trioxide rat, oral 14 mg/kg 0.014 [56]
Metallic Arsenic rat, intraperitoneal 13 mg/kg 0.013 [57]
Nicotine human, oralmice, oral 6.5–13.0 mg/kg (estimated)3.34 mg/kg 0.0065–0.0130.0034 [58][59]
Sodium cyanide rat, oral 6.4 mg/kg 0.0064 [60]
Hydrogen cyanide mouse, oral 3.7 mg/kg 0.0037 [61]
Chlorotoxin (CTX, from scorpions) mice 4.3 mg/kg 0.0043 [62]
White phosphorus rat, oral 3.03 mg/kg 0.00303 [63]
Strychnine human, oral 1–2 mg/kg (estimated) 0.001 [64]
Cantharidin (from blister beetles) human, oral 500 µg/kg 0.0005
Aflatoxin B1 (from Aspergillus flavus mold) rat, oral 480 µg/kg 0.00048 [65]
Plutonium dog, intravenous 320 µg/kg 0.00032 [66]
Amatoxin (from Amanita phalloides mushrooms) rat 300-700 µg/kg 0.0007 [67]
Tetrodotoxin (TTX, from blue-ringed octopus) mice, oral 334 µg/kg 0.000334 [68]
Bufotoxin (from Bufo toads) cat, intravenous 300 µg/kg 0.000300 [69]
Robustoxin (from Sydney funnel-web spider) mice 150 µg/kg 0.000150 [70]
Venom of the Brazilian wandering spider rat, subcutaneous 134 µg/kg 0.000134 [71]
Uranium mice, oral 114 µg/kg (estimated) 0.000114 [72]
Venom of the Inland Taipan (Australian snake) rat, subcutaneous 25 µg/kg 0.000025 [73]
Ricin (from castor oil plant) rat, intraperitoneal
rat, oral
22 μg/kg
20–30 mg/kg
0.000022
0.02
[74]
2,3,7,8-Tetrachlorodibenzodioxin (TCDD, in Agent Orange) rat, oral 20 µg/kg 0.00002 [75]
Sarin mouse, subcutaneous injection 17.23 µg/kg (estimated) 0.0000172 [76]
CrTX-A (from box jellyfish venom) crayfish, intraperitoneal 5 µg/kg 0.000005 [77]
Latrotoxin (from widow spider venom) mice 4.3 µg/kg 0.0000043 [78]
VX human, oral, inhalation, absorption through skin/eyes 2.3 µg/kg (estimated) 0.0000023 [79]
Batrachotoxin (from poison dart frog) human, sub-cutaneous injection 2–7 µg/kg (estimated) 0.000002 [80]
Abrin (from rosary pea) mice, intravenouslyhuman, inhalation

human, oral

0.7 µg/kg3.3 µg/kg

10–1000 µg/kg

0.00000070.0000033

0.00001–0.001

Maitotoxin (from ciguateric fish) mouse, intraperitoneal 0.13 µg/kg 0.00000013 [81]
Polonium-210 human, inhalation 10 ng/kg (estimated) 0.00000001 [82]
Diphtheria toxin mice 10 ng/kg 0.00000001 [83]
Shiga toxin (from dysentery) mice 2 ng/kg 0.000000002 [83]
Tetanospasmin (tetanus toxin) mice 2 ng/kg 0.000000002 [83]
Botulinum toxin (Botox) human, oral, injection, inhalation 1 ng/kg (estimated) 0.000000001 [84]
Ionizing radiation human, irradiation 5 Gy
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